Gendun Gyatso Palzangpo, also Gendun Gyatso (Tibetan: དགེ་འདུན་རྒྱ་མཚོ།, Wylie: dge-'dun rgya-mtsho "Sublimely Glorious Ocean of Spiritual Aspirants", layname: Yonten Phuntsok) (1475–1542) was considered posthumously to be the second Dalai Lama.
Gedun Gyatso became abbot of Tashilhunpo in 1512 at the age of thirty-six. In 1517 he became abbot of Drepung monastery and he revived the 'Great Prayer Festival' or Monlam Chenmo in 1518, presiding over the celebration with monks from the three large Gelug monasteries of Sera, Drepung and Gaden (Ganden was the original monastery of the Geluk order, founded by Je Tsongkhapa himself in 1409). He then became abbot of Sera monastery in 1525; Sera had been founded in 1419, by Jamchen Chojey (Sakya Yeshe), a disciple of Tsong Khapa.
His Seat has been Drepung.
He had no political power. The political role of the Dalai Lamas only began with the reign of the 5th Dalai Lama.